Stroke progresses in stages from ischemia to actual infarction. In most common situation i.e. ischemia occurs due to middle cerebral artery occlusion forming the densely ischemic central focus and a less densely ischemic “penumbra.” Cells within the central focus are usually damaged irreversibly unless reperfusion is quickly re-established, whereas cells within the penumbra may remain viable but at risk for several hours (30). When regional cerebral blood flow falls below 15-18 ml /100 g per minute, electrical activity within human neurons ceases. Further decrease results in decreased production of adenosine triphosphate which leads to anaerobic glycolysis resulting in metabolic acidosis and ischemic cascade. At our institution patients with acute emergencies viz head injury, trauma, as well as various paralytic conditions are submitted to CT examination.Our study constituted of 100 cases in 1 year presenting with the symptoms of cerbro vascular accidents who underwent CT examination. CT remains the predominant imaging modality for initial evaluation of patients with suspected stroke. Lesions that clinically can mimic ischemic stroke, such as hemorrhages, tumors, infections, vascular malformations, etc., can be excluded.
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